Mouse Hybridoma Development
With passion and know-how, InVivo has successfully realized more than 500 hybridoma development projects to date. The entire project, including mice immunization, cell fusion, screening, cloning and initial characterization of the developed monoclonal antibodies, usually takes around 22 weeks. For immunization ~ 5 mg of antigen (protein, peptide or hapten) is needed. In case the antigen (protein) is not available yet, InVivo can produce the protein of interest via expression in E. coli or via transient gene expression in HEK cells.
Advantages of the product
- Individualized screening
- Negative screening to avoid cross-reactions
- Isotyping and mycoplasma test